|
|
Problems of Drug Residues Determination in Waste Waters
Lisá, Hana ; Márová, Ivana (referee) ; Hajšlová, Jana (referee) ; Kráčmar, Stanislav (referee) ; Vávrová, Milada (advisor)
The PhD thesis deals with determination of sulfonamides and tetracyclines in waste waters. Sulphonamides and tetracyclines are widely used in human and veterinary medicine. They are biologically active compounds and block biological processes in waste water treatment plants. These substances can influence microorganisms in the environment. Sulphonamides and tetracyclines induce resistance in low concentrations. These substances penetrate into the environment from industrial production, use in households, hospitals, veterinary clinics and fish farms. Tetracyclines and sulphonamides were determined in waste water from waste water treatment plants in Brno. Optimalization of extraction of these compounds was performed by solid phase extraction. Sulphonamides and tetracyclines were determined by liquid chromatography coupled with diode array detector or coupled with mass spectrometry. Optimalized method was used for determination tetracyclines and sulphonamides in waste water from waste water treatment plants in Brno in years 2007 – 2010.
|
|
|
Application of separation methods for the determination of selected pharmaceuticals in waters
Burešová, Jitka ; Opatřilová, Radka (referee) ; Vávrová, Milada (advisor)
Antibiotics are widely used pharmaceuticals in human and veterinary medicine. These compounds are biologically active. They decrease efficiency of biological processes in wastewater treatment plants. Antibiotics are not eliminated from sewage water completely and they are discharged as contaminants into the receiving waters. Several methods exist for the determination of antibiotics in sewage water. In the first place liquid chromatography, gas chromatography and capillary electrophoresis are used. The aim of this thesis was to developed a suitable izolation technique and an optimal analytical method for identification and determination of penicillins in wastewater. For determination was selected amoxicillin, ampicillin and benzylpenicillin (penicillin G). These are very often used penicillins. An optimized method was used for determination of these penicilins in real samples from a wastewater treatment plant situated in Veterinary and pharmaceutical university in Brno and from the large-scale wastewater treatment plant in Brno-Modřice. Real samples were concentrated using SPE (solid phase extraction). For penicillins determination were used high performance liquid chromatography with diode array detection (HPLC/DAD).
|
|
|
Determination of selected drugs in water
Tran Xuan, Tiep ; Tulková, Tereza (referee) ; Vávrová, Milada (advisor)
Submitted thesis tackles the problem of numerous of antibiotics in waste water. Specifically, trimethroprim azithromycin and clarithomycin. In all of those cases we are dealing with a massive ecological threat at hand, causing harm to the enviroment. To isolation the specific kind of antibiotics the method of SPE was chosen by prior consultation with the supervisor. The method of high performance liquid chromatography with mass spectrometry detection was deemed superrior for the pinpointing of the exact pharmaceuticals in waste watters. The waste waters in and out flow was observed for twelve days with the maintainance of all necessary procedures listed above at water treatment plants Brno-Modřice.
|
|
|
Determination of selected drugs in water
Tran Xuan, Tiep ; Tulková, Tereza (referee) ; Vávrová, Milada (advisor)
Submitted thesis tackles the problem of numerous of antibiotics in waste water. Specifically, trimethroprim azithromycin and clarithomycin. In all of those cases we are dealing with a massive ecological threat at hand, causing harm to the enviroment. To isolation the specific kind of antibiotics the method of SPE was chosen by prior consultation with the supervisor. The method of high performance liquid chromatography with mass spectrometry detection was deemed superrior for the pinpointing of the exact pharmaceuticals in waste watters. The waste waters in and out flow was observed for twelve days with the maintainance of all necessary procedures listed above at water treatment plants Brno-Modřice.
|
|
|
Problems of Drug Residues Determination in Waste Waters
Lisá, Hana ; Márová, Ivana (referee) ; Hajšlová, Jana (referee) ; Kráčmar, Stanislav (referee) ; Vávrová, Milada (advisor)
The PhD thesis deals with determination of sulfonamides and tetracyclines in waste waters. Sulphonamides and tetracyclines are widely used in human and veterinary medicine. They are biologically active compounds and block biological processes in waste water treatment plants. These substances can influence microorganisms in the environment. Sulphonamides and tetracyclines induce resistance in low concentrations. These substances penetrate into the environment from industrial production, use in households, hospitals, veterinary clinics and fish farms. Tetracyclines and sulphonamides were determined in waste water from waste water treatment plants in Brno. Optimalization of extraction of these compounds was performed by solid phase extraction. Sulphonamides and tetracyclines were determined by liquid chromatography coupled with diode array detector or coupled with mass spectrometry. Optimalized method was used for determination tetracyclines and sulphonamides in waste water from waste water treatment plants in Brno in years 2007 – 2010.
|
|
|
Application of separation methods for the determination of selected pharmaceuticals in waters
Burešová, Jitka ; Opatřilová, Radka (referee) ; Vávrová, Milada (advisor)
Antibiotics are widely used pharmaceuticals in human and veterinary medicine. These compounds are biologically active. They decrease efficiency of biological processes in wastewater treatment plants. Antibiotics are not eliminated from sewage water completely and they are discharged as contaminants into the receiving waters. Several methods exist for the determination of antibiotics in sewage water. In the first place liquid chromatography, gas chromatography and capillary electrophoresis are used. The aim of this thesis was to developed a suitable izolation technique and an optimal analytical method for identification and determination of penicillins in wastewater. For determination was selected amoxicillin, ampicillin and benzylpenicillin (penicillin G). These are very often used penicillins. An optimized method was used for determination of these penicilins in real samples from a wastewater treatment plant situated in Veterinary and pharmaceutical university in Brno and from the large-scale wastewater treatment plant in Brno-Modřice. Real samples were concentrated using SPE (solid phase extraction). For penicillins determination were used high performance liquid chromatography with diode array detection (HPLC/DAD).
|
|
| |
guest ::
